Fractional excretion of uric acid: FJHN / gout / hereditary renal hypouricaemia

Description: 
The fractional excretion of uric acid collection is decreased in gout and familial juvenile hyperuricaemia, also known as autosomal dominant tubulointerstitial kidney disease (ADTKD).
Clinical details: 
The fractional excretion of uric acid (FEur) is decreased in under-excreting gout and autosomal dominant tubulointerstitial kidney disease. FEur may be dramatically increased in patients with hereditary renal hypouricaemia.
Related condition or disease: 
Gout, FJHN, autosomal dominant tubulointerstitial kidney disease, hereditary renal hypouricaemia.
Reference range: 

Please contact the laboratory to discuss

Units: 
24h urine collection
Department: 
Reference Services
Location: 
Blackfriars Hub
Sample type and Volume required: 
EDTA (purple top) and Lithium heparin (green top), 24 h urine collected with thymol
Turnaround time: 
3 weeks
Criteria for acceptance / rejections of sample
Storage and transport: 
10ml aliquot of warmed ( sink of hot water, 30min), well mixed 24h urine, store in fridge or freezer, can thaw in 1st class post.
Contacts:
Purine Research Laboratory at Blackfriars Hub
020 4 591 0058
Reference Chemistry, 1st Floor Blackfriars Hub
41-43 Friars Bridge Court
Blackfriars Road
London
SE1 8NZ
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Purine Research Laboratory at Blackfriars Hub

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Last updated: 30/01/2026