Apoliprotein B-100

Description: 
Serum Apo A-1 and Apo B concentrations are recognised as better indicators of atherosclerotic risk than cholesterol and triglycerides alone. Atherosclerotic patients are better distinguished from normal individuals by the finding of increased plasma Apo B or decreased plasma Apo A-1 than by a raised LDL and low HDL. The ratio of the Apo A-1 to Apo B may provide a better index of cardiovascular risk than the individual values.
Clinical details: 
Apo B is central to lipoprotein transport and is essential for the secretion of Triglyceride (TG) rich lipoproteins from the liver and gut.
Related condition or disease: 
Cardiovascular disease.
Reference range: 

Hypobetalipoproteinaemia occurs at ApoB < 0.4 g/L Cardiovascular Risk increases with ApoB > 0.8 g/L

Units: 
g/L
Department: 
Diagnostic Immunology and Allergy Department
Location: 
Blackfriars Hub
Sample type and Volume required: 
Clotted (yellow SST tube). Serum.
Turnaround time: 
3 days
Special sample instructions: 

Seat the patient 5 minutes before sampling. Fasting sample preferred, but non-fasting acceptable. Patient should follow their normal diet for 3 weeks prior to sampling.

Criteria for acceptance / rejections of sample
Contacts:
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Diagnostic Immunology Laboratory at Blackfriars Hub

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Last updated: 21/04/2026